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1

Flt3 ligand supports the differentiation of early B cell progenitors in the presence of interleukin-11 and interleukin-7

Robert J. Ray, Christopher J. Paige, Caren Furlonger, Stewart D. Lyman, Robert Rottapel

Journal:

European Journal of Immunology

Année:

1996

Langue:

english

Fichier:

PDF, 848 KB

english, 1996

2

Regulation of cytokine receptor signaling by SOCS1

Subburaj Ilangumaran, Robert Rottapel

Journal:

Immunological Reviews

Année:

2003

Langue:

english

Fichier:

PDF, 876 KB

english, 2003

3

Putting out the fire: coordinated suppression of the innate and adaptive immune systems by SOCS1 and SOCS3 proteins

Ioannis D. Dimitriou, Liliana Clemenza, Andrew J. Scotter, Grace Chen, Fiona M. Guerra, Robert Rottapel

Journal:

Immunological Reviews

Année:

2008

Langue:

english

Fichier:

PDF, 454 KB

english, 2008

4

Binding of phosphatidyl-inositol-3-OH kinase to CD28 is required for T-cell signalling

Pagès, Françoise, Ragueneau, Marguerite, Rottapel, Robert, Truneh, Alemseged, Nunes, Jacques, Imbert, Jean, Olive, Daniel

Journal:

Année:

1994

Fichier:

PDF, 448 KB

1994

5

10.1038/86327

Okkenhaug, Klaus, Wu, Linda, Garza, Kristine M., La Rose, Jose, Khoo, Wilson, Odermatt, Bernhard, Mak, Tak W., Ohashi, Pamela S., Rottapel, Robert

Journal:

Nature Immunology

Année:

2001

Langue:

english

Fichier:

PDF, 371 KB

english, 2001

6

Lfc and Tctex-1 regulate the genesis of neurons from cortical precursor cells

Gauthier-Fisher, Andrée, Lin, Dan C, Greeve, Melissa, Kaplan, David R, Rottapel, Robert, Miller, Freda D

Journal:

Nature Neuroscience

Année:

2009

Langue:

english

Fichier:

PDF, 1.35 MB

english, 2009

7

The tumor suppressor activity of SOCS-1

Rottapel, Robert, Ilangumaran, Subburaj, Neale, Christopher, La Rose, Jose, Ho, Jenny M-Y, Nguyen, Melody H-H, Barber, Dwayne, Dubreuil, Patrice, de Sepulveda, Paulo

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 361 KB

english, 2002

8

Signal transduction by several KIT juxtamembrane domain mutations

Casteran, Nathalie, De Sepulveda, Paulo, Beslu, Nathalie, Aoubala, Mustapha, Letard, Sébastien, Lecocq, Eric, Rottapel, Robert, Dubreuil, Patrice

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 425 KB

english, 2003

9

Flow cytometric analysis of cytokine receptor signal transduction

Subburaj Ilangumaran, Dina Finan, Robert Rottapel

Journal:

Journal of Immunological Methods

Année:

2003

Langue:

english

Fichier:

PDF, 535 KB

english, 2003

10

Expression of Flt3 tyrosine kinase receptor gene in mouse hematopoietic and nervous tissues

Odile deLapeyrière, Philippe Naquet, Jacqueline Planche, Sylvie Marchetto, Robert Rottapel, Danièle Gambarelli, Olivier Rosnet, Daniel Birnbaum

Journal:

Differentiation

Année:

1995

Langue:

english

Fichier:

PDF, 2.11 MB

english, 1995

11

Structural Basis and Sequence Rules for Substrate Recognition by Tankyrase Explain the Basis for Cherubism Disease

Sebastian Guettler, Jose LaRose, Evangelia Petsalaki, Gerald Gish, Andy Scotter, Tony Pawson, Robert Rottapel, Frank Sicheri

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 2.53 MB

english, 2011

12

Structural Basis and Sequence Rules for Substrate Recognition by Tankyrase Explain the Basis for Cherubism Disease

Sebastian Guettler, Jose LaRose, Evangelia Petsalaki, Gerald Gish, Andy Scotter, Tony Pawson, Robert Rottapel, Frank Sicheri

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 33 KB

english, 2012

13

Mechanistic Insight into the Microtubule and Actin Cytoskeleton Coupling through Dynein-Dependent RhoGEF Inhibition

David Meiri, Christopher B. Marshall, Melissa A. Greeve, Bryan Kim, Marc Balan, Fernando Suarez, Chris Bakal, Chuanjin Wu, Jose LaRose, Noah Fine, Mitsuhiko Ikura, Robert Rottapel

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 2.38 MB

english, 2012

14

Mechanistic Insight into the Microtubule and Actin Cytoskeleton Coupling through Dynein-Dependent RhoGEF Inhibition

David Meiri, Christopher B. Marshall, Melissa A. Greeve, Bryan Kim, Marc Balan, Fernando Suarez, Chris Bakal, Chuanjin Wu, Jose LaRose, Noah Fine, Mitsuhiko Ikura, Robert Rottapel

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 47 KB

english, 2012

15

Regulation of the immune system by SOCS family adaptor proteins

Subburaj Ilangumaran, Sheela Ramanathan, Robert Rottapel

Journal:

Seminars in Immunology

Année:

2004

Langue:

english

Fichier:

PDF, 371 KB

english, 2004

16

Adaptor Function for the Syk Kinases–Interacting Protein 3BP2 in IL-2 Gene Activation

Marcel Deckert, Sophie Tartare-Deckert, Jerry Hernandez, Robert Rottapel, Amnon Altman

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 379 KB

english, 1998

17

Regulation of NF-κB Signaling by Pin1-Dependent Prolyl Isomerization and Ubiquitin-Mediated Proteolysis of p65/RelA

Akihide Ryo, Futoshi Suizu, Yasuhiro Yoshida, Kilian Perrem, Yih-Cherng Liou, Gerburg Wulf, Robert Rottapel, Shoji Yamaoka, Kun Ping Lu

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2003

18

Probing the GTPase cycle with real-time NMR: GAP and GEF activities in cell extracts

Christopher B. Marshall, David Meiri, Matthew J. Smith, Mohammad T. Mazhab-Jafari, Geneviève M.C. Gasmi-Seabrook, Robert Rottapel, Vuk Stambolic, Mitsuhiko Ikura

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.35 MB

english, 2012

19

Socs1 binds to multiple signalling proteins and suppresses Steel factor-dependent proliferation

Sepulveda, Paulo De, Okkenhaug, Klaus, Rose, Jose La, Hawley, Robert G., Dubreuil, Patrice, Rottapel, Robert

Journal:

The EMBO Journal

Année:

1999

Langue:

english

Fichier:

PDF, 496 KB

english, 1999

20

The Mouse W/c-kit Locus : A Mammalian Gene That Controls the Development of Three Distinct Cell Lineages

PATRICE DUBREUIL, ROBERT ROTTAPEL, ALASTAIR D. REITH, LESLEY FORRESTER, ALAN BERNSTEIN

Journal:

Annals of the New York Academy of Sciences

Année:

1990

Langue:

english

Fichier:

PDF, 424 KB

english, 1990

21

CaPSID: A bioinformatics platform for computational pathogen sequence identification in human genomes and transcriptomes

Ivan Borozan, Shane Wilson, Paola Blanchette, Philippe Laflamme, Stuart N Watt, Paul M Krzyzanowski, Fabrice Sircoulomb, Robert Rottapel, Philip E Branton, Vincent Ferretti

Journal:

BMC Bioinformatics

Année:

2012

Langue:

english

Fichier:

PDF, 918 KB

english, 2012

22

Is there any relation between CD81 polymorphisms, HCV and the presence of cryoglobulinemia?

Joshi, Supriya, Schimmer, Joshua, Heathcote, Elizabeth J., Rottapel, Robert

Journal:

Gastroenterology

Année:

2003

Langue:

english

Fichier:

PDF, 183 KB

english, 2003

23

Mechanistic insight into GPCR-mediated activation of the microtubule-associated RhoA exchange factor GEF-H1

Meiri, David, Marshall, Christopher B., Mokady, Daphna, LaRose, Jose, Mullin, Michael, Gingras, Anne-Claude, Ikura, Mitsuhiko, Rottapel, Robert

Journal:

Nature Communications

Année:

2014

Langue:

english

Fichier:

PDF, 3.96 MB

english, 2014

24

Loss of SH3 Domain-Binding Protein 2 Function Suppresses Bone Destruction in Tumor Necrosis Factor-Driven and Collagen-Induced Arthritis in Mice

Mukai, Tomoyuki, Gallant, Richard, Ishida, Shu, Kittaka, Mizuho, Yoshitaka, Teruhito, Fox, David A., Morita, Yoshitaka, Nishida, Keiichiro, Rottapel, Robert, Ueki, Yasuyoshi

Journal:

Arthritis & Rheumatology

Année:

2015

Langue:

english

Fichier:

PDF, 1.39 MB

english, 2015

25

3BP2 Adapter Protein Is Required for Receptor Activator of NFκB Ligand (RANKL)-induced Osteoclast Differentiation of RAW264.7 Cells

GuezGuez, Amel, Prod'homme, Virginie, Mouska, Xavier, Baudot, Alice, Blin-Wakkach, Claudine, Rottapel, Robert, Deckert, Marcel

Journal:

Journal of Biological Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 5.20 MB

english, 2010

26

Insights into the binding of PARP inhibitors to the catalytic domain of human tankyrase-2

Qiu, Wei, Lam, Robert, Voytyuk, Oleksandr, Romanov, Vladimir, Gordon, Roni, Gebremeskel, Simon, Vodsedalek, Jakub, Thompson, Christine, Beletskaya, Irina, Battaile, Kevin P., Pai, Emil F., Rottapel, R

Journal:

Acta Crystallographica Section D Biological Crystallography

Année:

2014

Langue:

english

Fichier:

PDF, 1.86 MB

english, 2014

27

The c-fms Gene Complements the Mitogenic Defect in Mast Cells Derived from Mutant W Mice but Not mi (Microphthalmia) Mice

Patrice Dubreuil, Lesley Forrester, Robert Rottapel, Michael Reedijk, Jun Fujita and Alan Bernstein

Journal:

Proceedings of the National Academy of Sciences

Année:

1991

Langue:

english

Fichier:

PDF, 943 KB

english, 1991

28

SHP-1 Binds and Negatively Modulates the c-Kit Receptor by Interaction with Tyrosine 569 in the c-Kit Juxtamembrane Domain

Kozlowski, Maya, Larose, Louise, Lee, Fai, Le, Duc Mingh, Rottapel, Robert, Siminovitch, Katherine A.

Journal:

Molecular and Cellular Biology

Année:

1998

Langue:

english

Fichier:

PDF, 1.05 MB

english, 1998

29

SH3BP2 Cherubism Mutation Potentiates TNF-α-Induced Osteoclastogenesis via NFATc1 and TNF-α-Mediated Inflammatory Bone Loss

Mukai, Tomoyuki, Ishida, Shu, Ishikawa, Remi, Yoshitaka, Teruhito, Kittaka, Mizuho, Gallant, Richard, Lin, Yi-Ling, Rottapel, Robert, Brotto, Marco, Reichenberger, Ernst J, Ueki, Yasuyoshi

Journal:

Journal of Bone and Mineral Research

Année:

2014

Langue:

english

Fichier:

PDF, 11.32 MB

english, 2014

30

GEF-H1 is necessary for neutrophil shear stress–induced migration during inflammation

Fine, Noah, Dimitriou, Ioannis D., Rullo, Jacob, Sandí, María José, Petri, Björn, Haitsma, Jack, Ibrahim, Hisham, La Rose, Jose, Glogauer, Michael, Kubes, Paul, Cybulsky, Myron, Rottapel, Robert

Journal:

The Journal of Cell Biology

Année:

2016

Langue:

english

Fichier:

PDF, 2.04 MB

english, 2016

31

Expression and Signal Transduction of the FLT3 Tyrosine Kinase Receptor

Rosnet, Olivier, Bühring, Hans-Jörg, deLapeyrière, Odile, Beslu, Nathalie, Lavagna, Chrystel, Marchetto, Sylvie, Rappold, Irene, Drexler, Hans.G., Birg, Françoise, Rottapel, Robert, Hannum, Charles, D

Journal:

Acta Haematologica

Année:

2009

Fichier:

PDF, 2.43 MB

2009

32

Novel Biosensor Design Reveals the Role and Regulation of GEF-H1 in Cell Migration

Azoitei, Mihai L., Noh, Jungsik, Sandi, Maria J., Roudot, Philippe, Rottapel, Robert, Danuser, Gaudenz, Hahn, Klaus M.

Journal:

Biophysical Journal

Année:

2017

Langue:

english

Fichier:

PDF, 42 KB

english, 2017

33

Co-dependency between KRAS addiction and ARHGEF2 promotes an adaptive escape from MAPK pathway inhibition

Kent, Oliver A., Sandi, Maria-Jose, Rottapel, Robert

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 962 KB

english, 2017

34

Enhancing yoga participation: A qualitative investigation of barriers and facilitators to yoga among predominantly racial/ethnic minority, low-income adults

Spadola, Christine E., Rottapel, Rebecca, Khandpur, Neha, Kontos, Emily, Bertisch, Suzanne M., Johnson, Dayna A., Quante, Mirja, Khalsa, Sat Bir S., Saper, Robert B., Redline, Susan

Journal:

Complementary Therapies in Clinical Practice

Année:

2017

Langue:

english

Fichier:

PDF, 901 KB

english, 2017

35

Go with the flow: GEF-H1 mediated shear stress mechanotransduction in neutrophils

Fine, Noah, Dimitriou, Ioannis D., Rottapel, Robert

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 655 KB

english, 2017

36

Multiplexed real-time NMR GTPase assay for simultaneous monitoring of multiple GEF activities from human cancer cells and organoids

Gebregiworgis, Teklab, Marshall, Christopher Boyd, Nishikawa, Tadateru, Radulovich, Nikolina, Sandi, María-José, Fang, Zhenhao, Rottapel, Robert, Tsao, Ming-Sound, Ikura, Mitsuhiko

Journal:

Journal of the American Chemical Society

Année:

2018

Langue:

english

Fichier:

PDF, 677 KB

english, 2018

37

Intra-Articular Fms-Like Tyrosine Kinase 3 Ligand Expression Is a Driving Force in Induction and Progression of Arthritis

Dehlin, Mats, Bokarewa, Maria, Rottapel, Robert, Foster, Simon J., Magnusson, Mattias, Dahlberg, Leif E., Tarkowski, Andrej, Unutmaz, Derya

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 235 KB

english, 2008

38

Homeodomain-Interacting Protein Kinase (HIPK)-1 Is Required for Splenic B Cell Homeostasis and Optimal T-Independent Type 2 Humoral Response

Guerra, Fiona M., Gommerman, Jennifer L., Corfe, Steven A., Paige, Christopher J., Rottapel, Robert, Kanellopoulos, Jean

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 2.83 MB

english, 2012

39

Timed Regulation of 3BP2 Induction Is Critical for Sustaining CD8 + T Cell Expansion and Differentiation

Dimitriou, Ioannis D., Lee, Korris, Akpan, Itoro, Lind, Evan F., Barr, Valarie A., Ohashi, Pamela S., Samelson, Lawrence E., Rottapel, Robert

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 3.42 MB

english, 2018

40

The Mitotic Spindle Orientation Factor Lfc/Arhgef2 is Essential for Hematopoietic Stem Cell Function

Chan, Derek, Vujovic, Ana, de Rooij, Laura, Wong, Nicholas, Joyce, Cailin, Sandi, Maria, La Rose, Jose, Novina, Carl, Rottapel, Robert, Hope, Kristin

Journal:

Experimental Hematology

Année:

2018

Langue:

english

Fichier:

PDF, 158 KB

english, 2018

41

Regional perturbation of gene transcription is associated with intrachromosomal rearrangements and gene fusion transcripts in high grade ovarian cancer

Krzyzanowski, Paul M., Sircoulomb, Fabrice, Yousif, Fouad, Normand, Josee, La Rose, Jose, E. Francis, Kyle, Suarez, Fernando, Beck, Tim, McPherson, John D., Stein, Lincoln D., Rottapel, Robert K.

Journal:

Scientific Reports

Année:

2019

Fichier:

PDF, 2.90 MB

2019

42

Alveolar bone protection by targeting the SH3BP2‐SYK axis in osteoclasts

Kittaka, Mizuho, Yoshimoto, Tetsuya, Schlosser, Collin, Rottapel, Robert, Kajiya, Mikihito, Kurihara, Hidemi, Reichenberger, Ernst J, Ueki, Yasuyoshi

Journal:

Journal of Bone and Mineral Research

Année:

2019

Langue:

english

Fichier:

PDF, 10.50 MB

english, 2019

43

Alveolar bone protection by targeting the SH3BP2‐SYK axis in osteoclasts

Kittaka, Mizuho, Yoshimoto, Tetsuya, Schlosser, Collin, Rottapel, Robert, Kajiya, Mikihito, Kurihara, Hidemi, Reichenberger, Ernst J, Ueki, Yasuyoshi

Journal:

Journal of Bone and Mineral Research

Année:

2019

Fichier:

PDF, 10.50 MB

2019

44

Chromosomal Instability and mTORC1 Activation through PTEN Loss Contribute to Proteotoxic Stress in Ovarian Carcinoma

Chui, M. Herman, Doodnauth, Sasha A., Erdmann, Natalie, Tiedemann, Rodger E., Sircoulomb, Fabrice, Drapkin, Ronny, Shaw, Patricia, Rottapel, Robert

Journal:

Cancer Research

Année:

2019

Langue:

english

Fichier:

PDF, 2.24 MB

english, 2019

45

The Shb scaffold binds the Nck adaptor protein, p120 RasGAP and Chimaerins and thereby facilitates heterotypic cell segregation by the receptor EphB2

Wagner, Melany J, Hsiung, Marilyn S, Gish, Gerald D, Bagshaw, Rick D, Doodnauth, Sasha Anita, Soliman, Mohamed A, JÃ¸rgensen, Claus, Tucholska, Monika, Rottapel, Robert

Journal:

Journal of Biological Chemistry

Année:

2020

Fichier:

PDF, 2.55 MB

2020

46

A Novel Role for NUAK1 in Promoting Ovarian Cancer Metastasis through Regulation of Fibronectin Production in Spheroids

Fritz, Jamie Lee, Collins, Olga, Saxena, Parima, Buensuceso, Adrian, Ramos Valdes, Yudith, Francis, Kyle E., Brown, Kevin R., Larsen, Brett, Colwill, Karen, Gingras, Anne-Claude, Rottapel, Robert, She

Journal:

Année:

2020

Fichier:

PDF, 2.30 MB

2020

47

The LUBAC participates in lysophosphatidic acid-induced NF-ÎºB activation

Douanne, Tiphaine, Chapelier, Sarah, Rottapel, Robert, Gavard, Julie, BidÃ¨re, Nicolas

Journal:

Cellular Immunology

Année:

2020

Fichier:

PDF, 1022 KB

2020

48

Rheumatic immune-related adverse events associated with cancer immunotherapy: A nationwide multi-center cohort

Roberts, Janet, Ennis, Daniel, Hudson, Marie, Ye, Carrie, Saltman, Alexandra, Rottapel, Robert, Pope, Janet, Hoa, Sabrina, Tisseverasinghe, Annaliese, Fifi-Mah, Aurore, Maltez, Nancy, Jamal, Shahin

Journal:

Autoimmunity Reviews

Année:

2020

Fichier:

PDF, 799 KB

2020

49

Nucleotide Binding, Evolutionary Insights, and Interaction Partners of the Pseudokinase Unc-51-like Kinase 4

Preuss, Franziska, Chatterjee, Deep, Mathea, Sebastian, Shrestha, Safal, St-Germain, Jonathan, Saha, Manipa, Kannan, Natarajan, Raught, Brian, Rottapel, Robert, Knapp, Stefan

Journal:

Année:

2020

Fichier:

PDF, 4.07 MB

2020